Target controlled infusion anaesthesia in children

Target Controlled Infusion (TCI)

Total Intravenous Anaesthesia in dogs: Development of a Target Controlled Infusion (TCI) scheme for propofol

Factors affecting recovery from anaesthesia with propofol–remifentanil target-controlled infusion in laparoscopic surgery

Objective This study was performed to analyse factors influencing the effect-site concentration (Ce) of propofol at return of consciousness (ROC) with target-controlled infusion of propofol-remifentanil after laparoscopic surgery. Methods In total, 112 patients who underwent laparoscopic surgery under general anaesthesia were given propofol at the target concentration of 3.5 µg/ml. Remifentanil...

Target-controlled infusion of propofol in dogs--evaluation of four targets for induction of anaesthesia.

Four groups of 20 dogs were anaesthetised by means of target-controlled infusions of propofol designed to achieve 2.5 microg/ml, 3.0 microg/ml, 3.5 microg/ml or 4.0 microg/ml of propofol in blood. The dogs' pulse rate and respiratory rate were recorded before premedication and induction, immediately after endotracheal intubation and three and five minutes later (times 0, 3 and 5, respectively),...

Migrating from target-controlled infusion to closed-loop control in general anaesthesia

The target-controlled infusion (TCI) technique has been successfully and commercially used in clinical general anaesthesia with the intravenous anaesthetic agent propofol. The technique is based on a population pharmacokinetic model and is an open-loop control system. Closed-loop control requires a reliable and consistent signal for feedback utilisation. With all anaesthetic agents the somatose...